Publications
Our teams aspire to make discoveries that impact everyone, and core to our approach is sharing our research and tools to fuel progress in the field.
Our teams aspire to make discoveries that impact everyone, and core to our approach is sharing our research and tools to fuel progress in the field.
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1 - 15 of 10327 publications
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Recent work suggested utilizing inference compute, showing that scaling of number of samples consistently improves the fractions of problems solved by any attempt, namely the coverage. In this work, we suggest that inference scaling gains should be compared with proper baselines, as some datasets become degenerate when allowing a large number of attempts. We focus on two domains - mathematical reasoning and factual knowledge, showing that for the MATH and Entity Questions datasets, informed answer enumeration obtains similar or even better results than repeated model sampling, with a much lower sample budget. While we believe that inference scaling is a promising approach for unlocking the potential of language models, we recommend carefully selecting models and datasets when applying this method. Otherwise, the results of inference scaling should be interpreted with caution.
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Passive Heart Rate Monitoring During Smartphone Use in Everyday Life
Shun Liao
Paolo Di Achille
Jiang Wu
Jonathan Wang
Eric Teasley
Lawrence Cai
Daniel McDuff
Hao-Wei Su
Brent Winslow
Anupam Pathak
Shwetak Patel
Jim Taylor
Jamie Rogers
(2025)
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Resting heart rate (RHR) is an important biomarker of cardiovascular health and mortality, but tracking it longitudinally generally requires a wearable device, limiting its availability. We present PHRM, a deep learning system for passive heart rate (HR) and RHR measurements during ordinary smartphone use, using facial video-based photoplethysmography. Our system was developed using 225,773 videos from 495 participants and validated on 185,970 videos from 205 participants in laboratory and free-living conditions – the largest validation study of its kind. Compared to reference electrocardiogram, PHRM achieved a mean absolute percentage error (MAPE) <10% for HR measurements across three skin tone groups of light, medium and dark pigmentation; MAPE for each skin tone group was non-inferior versus the others. Daily RHR measured by PHRM had a mean absolute error <5 bpm compared to a wearable HR tracker, and was associated with known risk factors. These results highlight the potential of smartphones to enable passive and equitable heart health monitoring.
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A Strategic Framework for AI Product Development and Evaluation in Enterprise Software
International Journal of Computer Engineering and Technology (IJCET), Volume 16, Issue 1 (2025)
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This article presents a comprehensive framework for developing and evaluating AI products in enterprise software systems, addressing the critical challenges organizations face during AI transformation initiatives. The article introduces a structured approach to decision-making for AI integration, encompassing ROI evaluation, user value assessment, and business impact analysis. It establishes distinct methodologies for both assistive and autonomous AI systems, providing detailed metrics for measuring success and performance across different implementation scenarios. Across various industries, the framework has shown potential in reducing implementation time, increasing user adoption rates, and enhancing overall project success rates, highlighting its practical applicability. The article methodology combines theoretical analysis with practical case studies, resulting in a flexible yet robust framework that can adapt to various organizational contexts. The framework's primary contribution lies in its practical approach to bridging the gap between theoretical AI capabilities and real-world implementation challenges, offering product leaders a systematic methodology for AI product development and evaluation. By addressing both current implementation challenges and future scalability requirements, this framework provides organizations with a foundational tool for navigating their AI transformation journey while maintaining a focus on measurable business outcomes and user value creation.
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Avoid global outages by partitioning cloud applications to reduce blast radius
Karan Anand
https://cloud.google.com/ (2025)
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Cloud application development faces the inherent challenge of balancing rapid innovation with high availability. This blog post details how Google Workspace's Site Reliability Engineering team addresses this conflict by implementing vertical partitioning of serving stacks. By isolating application servers and storage into distinct partitions, the "blast radius" of code changes and updates is significantly reduced, minimizing the risk of global outages. This approach, which complements canary deployments, enhances service availability, provides flexibility for experimentation, and facilitates data localization. While challenges such as data model complexities and inter-service partition misalignment exist, the benefits of improved reliability and controlled deployments make partitioning a crucial strategy for maintaining robust cloud applications
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TOKENFORMER: Rethinking Transformers Scaling with Tokenized Model Parameters
Haiyang Wang
Fan Yue
Jan Eric Lenssen
Liwei Wang
Bernt Schiele
2025
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Transformers have become the predominant architecture in foundation models due to their excellent performance across various domains. However, the substantial cost of scaling these models remains a significant concern. This problem arises primarily from their dependence on fixed parameters within linear projections, especially when architectural modifications (e.g., channel dimensions) are introduced. Each scaling iteration typically requires retraining the entire model from the beginning, leading to suboptimal utilization of computational resources. To overcome this limitation, we introduce TokenFormer, a naturally scalable architecture that leverages the attention mechanism exclusively for computations among input tokens and interactions between input tokens and model parameters, thereby enhancing architectural flexibility. By treating model parameters as tokens, we replace all the linear projections in Transformer with our token-parameter attention layer, where input tokens act as queries and model parameters as keys and values. This innovative approach allows for progressive and efficient scaling without necessitating retraining from scratch. Our model scales from 124 million to 1.4 billion parameters by incrementally adding new key-value parameters, achieving performance comparable to models trained from scratch while greatly reducing training costs. Code and models will be publicly available.
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AfriMed-QA: A Pan-African Multi-Specialty Medical Question-Answering Benchmark Dataset
Tobi Olatunji
Abraham Toluwase Owodunni
Charles Nimo
Jennifer Orisakwe
Henok Biadglign Ademtew
Chris Fourie
Foutse Yuehgoh
Stephen Moore
Mardhiyah Sanni
Emmanuel Ayodele
Timothy Faniran
Bonaventure F. P. Dossou
Fola Omofoye
Wendy Kinara
Tassallah Abdullahi
Michael Best
2025
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Recent advancements in large language model (LLM) performance on medical multiple-choice question (MCQ) benchmarks have stimulated significant interest from patients and healthcare providers globally. Particularly in low- and middle-income countries (LMICs) facing acute physician shortages and lack of specialists, LLMs offer a potentially scalable pathway to enhance healthcare access and reduce costs. However, LLM training data is sourced from predominantly Western text, existing benchmarks are predominantly Western-centric, limited to MCQs, and focused on a narrow range of clinical specialties, raising concerns about their applicability in the Global South, particularly across Africa where localized medical knowledge and linguistic diversity are often underrepresented. In this work, we introduce AfriMed-QA, the first large-scale multi-specialty Pan-African medical Question-Answer (QA) dataset designed to evaluate and develop equitable and effective LLMs for African healthcare. It contains 3,000 multiple-choice professional medical exam questions with answers and rationale, 1,500 short answer questions (SAQ) with long-from answers, and 5,500 consumer queries, sourced from over 60 medical schools across 15 countries, covering 32 medical specialties. We further rigorously evaluate multiple open, closed, general, and biomedical LLMs across multiple axes including accuracy, consistency, factuality, bias, potential for harm, local geographic relevance, medical reasoning, and recall. We believe this dataset provides a valuable resource for practical application of large language models in African healthcare and enhances the geographical diversity of health-LLM benchmark datasets.
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Context is Key for Agent Security
Lillian Tsai
Eugene Bagdasaryan
arXiv (2025)
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Judging the safety of an action, whether taken by a human or a system, must take into account the context in which the action takes place. For example, deleting an email from a user's mailbox may or may not be appropriate depending on the email's content, the user's goals, or even available space. Systems today that make these judgements---providing security against harmful or inappropriate actions---rely on manually-crafted policies or user confirmation for each relevant context. With the upcoming deployment of systems like generalist agents, we argue that we must rethink security designs to adapt to the scale of contexts and capabilities of these systems. As a first step, this paper explores contextual security in the domain of agents and proposes contextual security for agents (Conseca), a framework to generate just-in-time, contextual, and human-verifiable security policies.
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Online Bidding under RoS Constraints without Knowing the Value
Sushant Vijayan
Swati Padmanabhan
The Web Conference (2025)
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We consider the problem of auto-bidding in online advertising from the perspective of a single advertiser. The goal of the advertiser is to maximize their value under the Return-on-Spend (RoS) constraint, with performance measured in terms of \emph{regret} against the optimal offline solution that knows all queries a priori. Importantly, the value of the item is \textit{unknown} to the bidder ahead of time. The goal of the bidder is to quickly identify the optimal bid, while simultaneously satisfying budget and RoS constraints. Using a simple UCB-style algorithm, we provide the first result which achieves optimal regret and constraint violation for this problem.
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This invited OFC 2025 tutorial will review recent progress and scaling limitations of IM-DD-based low-cost optical interconnects. It will examine how datacenter-reach optimized coherent optics can address these challenges
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Performance of a Deep Learning Diabetic Retinopathy Algorithm in India
Arthur Brant
Xiang Yin
Lu Yang
Jay Nayar
Divleen Jeji
Sunny Virmani
Anchintha Meenu
Naresh Babu Kannan
Florence Thng
Lily Peng
Ramasamy Kim
JAMA Network Open (2025)
Preview abstract
Importance: While prospective studies have investigated the accuracy of artificial intelligence (AI) for detection of diabetic retinopathy (DR) and diabetic macular edema (DME), to date, little published data exist on the clinical performance of these algorithms.
Objective: To evaluate the clinical performance of an automated retinal disease assessment (ARDA) algorithm in the postdeployment setting at Aravind Eye Hospital in India.
Design, Setting, and Participants: This cross-sectional analysis involved an approximate 1% sample of fundus photographs from patients screened using ARDA. Images were graded via adjudication by US ophthalmologists for DR and DME, and ARDA’s output was compared against the adjudicated grades at 45 sites in Southern India. Patients were randomly selected between January 1, 2019, and July 31, 2023.
Main Outcomes and Measures: Primary analyses were the sensitivity and specificity of ARDA for severe nonproliferative DR (NPDR) or proliferative DR (PDR). Secondary analyses focused on sensitivity and specificity for sight-threatening DR (STDR) (DME or severe NPDR or PDR).
Results: Among the 4537 patients with 4537 images with adjudicated grades, mean (SD) age was 55.2 (11.9) years and 2272 (50.1%) were male. Among the 3941 patients with gradable photographs, 683 (17.3%) had any DR, 146 (3.7%) had severe NPDR or PDR, 109 (2.8%) had PDR, and 398 (10.1%) had STDR. ARDA’s sensitivity and specificity for severe NPDR or PDR were 97.0% (95% CI, 92.6%-99.2%) and 96.4% (95% CI, 95.7%-97.0%), respectively. Positive predictive value (PPV) was 50.7% and negative predictive value (NPV) was 99.9%. The clinically important miss rate for severe NPDR or PDR was 0% (eg, some patients with severe NPDR or PDR were interpreted as having moderate DR and referred to clinic). ARDA’s sensitivity for STDR was 95.9% (95% CI, 93.0%-97.4%) and specificity was 94.9% (95% CI, 94.1%-95.7%); PPV and NPV were 67.9% and 99.5%, respectively.
Conclusions and Relevance: In this cross-sectional study investigating the clinical performance of ARDA, sensitivity and specificity for severe NPDR and PDR exceeded 96% and caught 100% of patients with severe NPDR and PDR for ophthalmology referral. This preliminary large-scale postmarketing report of the performance of ARDA after screening 600 000 patients in India underscores the importance of monitoring and publication an algorithm's clinical performance, consistent with recommendations by regulatory bodies.
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Augmenting LLMs with context leads to improved performance across many applications. Despite much research on Retrieval Augmented Generation (RAG) systems, an open question is whether errors arise because LLMs fail to utilize the context from retrieval or the context itself is insufficient to answer the query. To shed light on this, we develop a new notion of sufficient context, along with a way to classify instances that have enough information to answer the query. We then use sufficient context to analyze several models and datasets. By stratifying errors based on context sufficiency, we find that proprietary LLMs (Gemini, GPT, Claude) excel at answering queries when the context is sufficient, but often output incorrect answers instead of abstaining when the context is not. On the other hand, open-source LLMs (Llama, Mistral, Gemma) hallucinate or abstain often, even with sufficient context. We further categorize cases when the context is useful, and improves accuracy, even though it does not fully answer the query and the model errs without the context. Building on our findings, we explore ways to reduce hallucinations in RAG systems, including a new selective generation method that leverages sufficient context information for guided abstention. Our method improves the fraction of correct answers among times where the model responds by 2--10% for Gemini, GPT, and Gemma.
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A Scalable Framework for Evaluating Health Language Models
Neil Mallinar
Tony Faranesh
Brent Winslow
Nova Hammerquist
Ben Graef
Cathy Speed
Mark Malhotra
Shwetak Patel
Xavi Prieto
Daniel McDuff
Ahmed Metwally
(2025)
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Large language models (LLMs) have emerged as powerful tools for analyzing complex datasets. Recent studies demonstrate their potential to generate useful, personalized responses when provided with patient-specific health information that encompasses lifestyle, biomarkers, and context. As LLM-driven health applications are increasingly adopted, rigorous and efficient one-sided evaluation methodologies are crucial to ensure response quality across multiple dimensions, including accuracy, personalization and safety. Current evaluation practices for open-ended text responses heavily rely on human experts. This approach introduces human factors and is often cost-prohibitive, labor-intensive, and hinders scalability, especially in complex domains like healthcare where response assessment necessitates domain expertise and considers multifaceted patient data. In this work, we introduce Adaptive Precise Boolean rubrics: an evaluation framework that streamlines human and automated evaluation of open-ended questions by identifying gaps in model responses using a minimal set of targeted rubrics questions. Our approach is based on recent work in more general evaluation settings that contrasts a smaller set of complex evaluation targets with a larger set of more precise, granular targets answerable with simple boolean responses. We validate this approach in metabolic health, a domain encompassing diabetes, cardiovascular disease, and obesity. Our results demonstrate that Adaptive Precise Boolean rubrics yield higher inter-rater agreement among expert and non-expert human evaluators, and in automated assessments, compared to traditional Likert scales, while requiring approximately half the evaluation time of Likert-based methods. This enhanced efficiency, particularly in automated evaluation and non-expert contributions, paves the way for more extensive and cost-effective evaluation of LLMs in health.
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From Few to Many: Self-Improving Many-Shot Reasoners Through Iterative Optimization and Generation
Han Zhou
Ke Jiang
International Conference on Learning Representations (ICLR) (2025) (to appear)
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Recent advances in long-context large language models (LLMs) have led to the emerging paradigm of many-shot in-context learning (ICL), where it is observed that scaling many more demonstrating examples beyond the conventional few-shot setup in the context can lead to performance benefits. However, despite its promise, it is unclear what aspects dominate the benefits and whether simply scaling to more examples is the most effective way of improving many-shot ICL. In this work, we first provide an analysis of the factors driving many-shot ICL, and we find that 1) many-shot performance can still be attributed to often a few disproportionately influential examples and 2) identifying such influential examples ("optimize") and using them as demonstrations to regenerate new examples ("generate") can lead to further improvements. Inspired by the findings, we propose BRIDGE, an algorithm that alternates between the optimize step with Bayesian optimization to discover the influential sets of examples and the generate step to reuse this set to expand the reasoning paths of the examples back to the many-shot regime automatically. On Gemini, Claude, and Mistral LLMs of different sizes, we show that BRIDGE to significant improvements across a diverse set of tasks, including symbolic reasoning, numerical reasoning, and code generation.
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InstructPipe: Generating Visual Blocks Pipelines with Human Instructions and LLMs
Zhongyi Zhou
Jing Jin
Xiuxiu Yuan
Jun Jiang
Jingtao Zhou
Yiyi Huang
Kristen Wright
Jason Mayes
Mark Sherwood
Alex Olwal
Ram Iyengar
Na Li
Proceedings of the 2025 CHI Conference on Human Factors in Computing Systems (CHI), ACM, pp. 23
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Visual programming has the potential of providing novice programmers with a low-code experience to build customized processing pipelines. Existing systems typically require users to build pipelines from scratch, implying that novice users are expected to set up and link appropriate nodes from a blank workspace. In this paper, we introduce InstructPipe, an AI assistant for prototyping machine learning (ML) pipelines with text instructions. We contribute two large language model (LLM) modules and a code interpreter as part of our framework. The LLM modules generate pseudocode for a target pipeline, and the interpreter renders the pipeline in the node-graph editor for further human-AI collaboration. Both technical and user evaluation (N=16) shows that InstructPipe empowers users to streamline their ML pipeline workflow, reduce their learning curve, and leverage open-ended commands to spark innovative ideas.
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Generative AI for medical education: Insights from a case study with medical students and an AI tutor for clinical reasoning
Amy Wang
Roma Ruparel
Paul Jhun
Julie Anne Seguin
Patricia Strachan
Renee Wong
2025
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Generative Artificial Intelligence (AI), particularly Large Language Models (LLMs), have demonstrated significant potential in clinical reasoning skills such as history-taking and differential diagnosis generation—critical aspects of medical education. This work explores how LLMs can augment medical curricula through interactive learning. We conducted a participatory design process with medical students, residents and medical education experts to co-create an AI-powered tutor prototype for clinical reasoning. As part of the co-design process, we conducted a qualitative user study, investigating learning needs and practices via interviews, and conducting concept evaluations through interactions with the prototype. Findings highlight the challenges learners face in transitioning from theoretical knowledge to practical application, and how an AI tutor can provide personalized practice and feedback. We conclude with design considerations, emphasizing the importance of context-specific knowledge and emulating positive preceptor traits, to guide the development of AI tools for medical education.
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